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Analytical confirmation relies on HPLC at minimum, with mass spectrometry applied where peptide identity needs orthogonal confirmation

& Koumura, T

These IR-induced mitochondrial defects are evident in both insulin-sensitive tissues (liver, muscle) and in the heart and brain, providing a mechanistic link between metabolic dysfunction and cardiovascularcognitive comorbidity

It may be useful in acute paracetamol overdoses that present to primary care facilities within 2 h of ingestion (or 4 h for massive overdoses or exposures to MR/ER preparations) [Citation74]